Spint1-as1
WebJan 1, 2024 · In addition, SPINT1-AS1 has been shown to be associated with hormone resistance. High levels of SPINT1-AS1 can be a biomarker sensitive to Lapatinib in NCI … WebThe high-affinity IgE receptor gamma subunit gene (FCER1G) plays a pivotal role in allergic inflammatory signaling, which is closely associated with allergic reactions. Previous studies have shown that FCER1G is an innate immunity gene and is involved in the development of many diseases. However, the role of FCER1G in pan-cancer has not been fully studied.
Spint1-as1
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WebFeb 9, 2024 · Genes in cluster 3 (PTPN3, one transcript of SPINT1-AS1, SPINT1, ST14, and ESRP1) were primarily responsible for epithelial cell development and differentiation. The miRNAs (miR-337-3p and miR-202-5p) were identified to play important roles in the tumor endothelial-mesenchymal transition process. WebJul 10, 2024 · Dual luciferase reporter assay. Luciferase reporter gene vectors were constructed with SPINT1 mRNA 5′UTR sequences or mutant 5′UTR sequences in pGL3 plasmids (RiboBio, Guangzhou, China). The SPINT1-AS1 sequence was subcloned into the pcDNA3.1 vector (RiboBio), and an empty pcDNA3.1 vector was used as a control. SW480 …
WebJan 1, 2024 · LncRNA SPINT1-AS1 (serine peptidase inhibitor, Kunitz Type 1 antisense RNA1) is a member of the Kunitz family of serine protease inhibitors. The Kunitz family, … WebApr 26, 2024 · Consistently, SPINT1-AS1 knockdown abolished CRC tumorigenesis manifested as inhibited cell proliferation and autophagy, as well as promoted apoptosis. Interestingly, SPINT1 mRNA overexpression led to the same phenotypes as SPINT1-AS1 knockdown in CRC cells. In addition, exosome-mediated SPINT1-AS1 transfer promoted …
WebBlue Cross Blue Shield of Massachusetts provides a Summary of Benefits and Coverage (SBC) with online access to the corresponding coverage policy to all of our fully insured … WebSPINT1-AS1:SPINT1 antisense RNA 1 RP11-532F12.5 . Function. RP11-532F12.5 might regulate the expression of neighboring protein-coding genes and influence the …
WebSPINT1-AS1 was a sensitive biomarker of NCI-N87 and MCF7 cancer cells to Lapatinib. In conclusions, lncRNAs GIHCG and SPINT1-AS1 were involved in regulating Lapatinib sensitivity. Up-regulation of ...
WebJan 1, 2024 · LncRNA SPINT1-AS1 (serine peptidase inhibitor, Kunitz Type 1 antisense RNA1) is a member of the Kunitz family of serine protease inhibitors. The Kunitz family, which is abnormally expressed in a great diversity of cancers, inhibits the activity of a variety of proteases including hepatocyte growth factor (HGF) activators, stromal enzymes and … crpf application last dateWebNov 12, 2024 · The SPINT1-AS1 promoted the progression of breast cancer by regulating miR-let-7a/b/i-5p . In contrast, LINC00861 could inhibit cervical cancer's progression by competitively sponging miR‑513b‑5p . The LINC01094 promotes ccRCC development by miR-224-5p/CHSY1 or upregulating SLC2A3 via microRNA-184 [59, 60]. However, only a … crpf asi applyWebNov 1, 2024 · SPINT1-AS1 promoter Wt/Mut were sub-cloned into the pGL3 vector (Promega, Madison, WI), followed by co-transfection into CRC cells along with pcDNA3.1/E2F3 or pcDNA3.1. Similarly, the fragments of SPINT1-AS1 or E2F3 mRNA with wild-type and mutant type miR-433–3p binding sites were inserted into pmirGLO dual … crpf asi full form