Webb28 juni 2024 · Thus, SLRP biglycan is a potential marker which is significantly altered in different clinicopathological states. Small leucine-rich proteoglycans (SLRPs) are … Webb3 jan. 2006 · A major and early feature of cartilage degeneration is proteoglycan breakdown. Matrix metalloprotease (MMP)-13 plays an important role in cartilage …
Biglycan: an emerging small leucine-rich proteoglycan …
WebbKEGG Orthology (KO) [BR:agen00001] 09180 Brite Hierarchies 09183 Protein families: signaling and cellular processes 00535 Proteoglycans [BR:agen00535] 126034351 WebbThis gene encodes a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. In these bifunctional molecules, the protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings. the phoenix rise recover live
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Webb28 juni 2024 · Extracellular matrix (ECM) plays an important role in the structural organization of tissue and delivery of external cues to the cell. Biglycan, a class I small leucine-rich proteoglycans (SLRP), is a key component of the ECM that participates in scaffolding the collagen fibrils and mediates cell signaling. Dysregulation of biglycan … WebbBiglycan (BGN), a proteoglycan of the extracellular matrix, is included in mRNA signatures for prostate cancer aggressiveness. To understand the impac… WebbThe small leucine-rich PG (SLRP) family is comprised of 17 gene products, some of which are not true PGs. Among these are biglycan, decorin, lumican, fibromodulin, keratocan, … sick leave and personal leave difference