WebMar 16, 2024 · Phosphating is a conversion coating that is applied to steel or iron components, and is mostly used as a pretreatment method in conjunction with another … WebFrom these, we characterized the phospeptin and pythonamide pathways, revealing cases of unusual bioactive compound structure and enzymology, respectively. Together, this research demonstrates how microbiomics-driven strategies can enable the investigation of previously undescribed enzymes and natural products in underexplored microbial groups ...
Biosynthetic potential of the global ocean microbiome
WebAmong these molecules, nonribosomal peptides (NRPs) represent a diverse class of natural products that include antibiotics, immunosuppressants, and anticancer agents. Recent … WebFrom these, we characterized the phospeptin and pythonamide pathways, revealing cases of unusual bioactive compound structure and enzymology, respectively. Together, this research demonstrates how microbiomics-driven strategies can enable the investigation of previously undescribed enzymes and natural products in underexplored microbial groups ... earth science modules pdf
Publications of Bork Group
WebNature 2024 07 22;607(7917):111-118. Epub 2024 Jun 22. Structural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany. Natural microbial communities are phylogenetically and metabolically diverse. In addition to underexplored organismal groups Our work provides an unprecedented picture of the biosynthetic activities of microbes in the world’s oceans. It generates an atlas to guide future research in fields including marine ecology, evolution, biotechnology and natural-product drug discovery. We also demonstrated that combined computational and molecular … See more The ocean covers 71% of Earth’s surface and contains 97% of its water. Each drop of seawater contains thousands of microbial cells — … See more Thanks to decades of ocean sampling, such as that done by the Tara Oceans expedition4, we were able to analyse metagenomes from more than 1,000 water samples … See more For the past two decades, scientists around the globe have been sampling and sequencing the DNA of marine microbes as part of expeditions … See more earth science minor ucsb