WebNov 3, 2024 · NEJM, 2001. MRCT. normothermia vs moderate hypothermia (T33 C for 48 hours) improved ICP but no reduction in mortality. patients > 45 years do worse with induced hypothermia. if a patient arrives hypothermic -> do not warm to 37 (poorer outcome) if a patient arrives hypothermic -> they will have a significantly worse TBI. WebJun 17, 2024 · At 6 months, 465 of 925 patients (50%) in the hypothermia group had died, as compared with 446 of 925 (48%) in the normothermia group (relative risk with hypothermia, 1.04; 95% confidence interval [CI], 0.94-1.14; p = 0.37). Of the 1,747 patients in whom the functional outcome was assessed, 488 of 881 (55%) in the hypothermia …
Errors in Secondary Outcomes JAMA JAMA Network
WebJun 16, 2024 · No Benefit to Hypothermia Compared with Normothermia After Cardiac Arrest. Mortality and neurological outcomes were similar when targets were 33°C or 37.5°C. Nearly 2 decades ago, the concept of “therapeutic hypothermia” was introduced into the care of patients with coma after cardiac arrest ( NEJM JW Gen Med Mar 15 2002 and N … WebCompared with the Targeted Hypothermia versus Targeted Normothermia after Out-of-Hospital Cardiac Arrest (TTM2) trial, 8 it is difficult to extrapolate the data to the patients enrolled in the current trial because the 2 populations are not comparable in terms of cardiogenic shock incidence (100% in the current trial vs 29%-35% in the TTM2 trial), … br2335 battery replacement
Hypothermia versus normothermia after out-of-hospital cardiac …
WebJun 17, 2024 · The trial asked whether there was benefit from hypothermia (33C) when compared to enforced normothermia (36C). The trial was modern, methodologically robust, and large (involving 950 patients – compared to 220 patients in HACA and Bernard et al. combined). The patient outcomes in both arms of the TTM trial were essentially the … WebOf the 1747 patients in whom the functional outcome was assessed, 488 of 881 (55%) in the hypothermia group had moderately severe disability or worse (modified Rankin scale score ≥4), as compared with 479 of 866 (55%) in the normothermia group (relative risk with hypothermia, 1.00; 95% CI, 0.92 to 1.09). WebThe New England Journal of Medicine br 2325 rayovac lithium batteries