WebTransfectant HeLa cells were generated that expressed human ferritin H-chain wild type and an H-chain mutant with inactivated ferroxidase activity under the control of the … WebThe iron-storage protein ferritin consists of a protein shell and has an iron content of up to 4500 iron atoms as a microcrystalline ferric oxide hydrate. A study was made of the uptake of ferrous iron by apoferritin in the presence of an oxidizing agent at very low iron:protein ratios. At ratios of less than about 150 iron atoms per apoferritin molecule hyperbolic …

Synthesis, characterization and application of magnetoferritin ...

Web20 dec. 1990 · Ferritin is important in iron homeostasis. Its twenty-four chains of two types, H and L, assemble as a hollow shell providing an iron-storage cavity. Ferritin molecules … Web3 okt. 2011 · Expression of human H-chain ferritin can be used to generate contrast in T2 weighted MRI in vivo, , , , , , , , , causing a local reduction in the signal intensity. The iron … himeros racehorse

Expression, purification, and characterization of recombinant …

Web23 nov. 2016 · Human ferritins have been extensively studied to be used as nanocarriers for diverse applications and could represent a convenient alternative for targeted delivery of … WebFerritin stores iron as ferrihydrite inside a shell composed of H and L protein chains. H chains contain ferroxidase centres catalysing Fe2+ oxidation, while L chains lack these centres but seem to promote ferrihydrite nucleation. Mossbauer spectroscopic studies of recombinant H-chain ferritins show the following: (1) fast Fe2+ oxidation is associated … Web15 jun. 1993 · In most vertebrates the ferritins are composed of various proportions of two subunit types, H and L chains, genetically distinct and with about 50% sequence identity … home improvement store in ridgeland